Several studies have noted an association between exercise related PVCs and coronary artery disease. One of these involved military veterans, mostly male and 60+ years of age, of whom roughly 25% were treated for heart disease (1).
In this group, frequent exercise PVCs proved an additional risk factor for heart disease, whether during exercise or afterwards, not unlike many other cardiac risk factors such as smoking, hypertension, high cholesterol, obesity and/or diabetes.
Most patients with PVCs and otherwise normal heart function, a normal EKG and echo don’t need treatment, other than perhaps a beta blocker to reduce their frequency, and are thus perfectly safe to exercise.
- Ventricular Arrhythmias During Clinical Treadmill Testing and Prognosis. Frederick E. Dewey, BA et al; Arch Intern Med. 2008;168(2):225-234. doi:10.1001/archinte.168.2.225
- Association of Exercise Capacity on Treadmill With Future Cardiac Events in Patients Referred for Exercise Testing. Pamela N. Peterson, MD, et al; Arch Intern Med. 2008;168(2):174-179. doi:10.1001/archinternmed.2007.68.