Submitted by Dr T on October 14, 2012 – 9:35am
Before I answer your question, please remember this, your husband still has heart disease. The real question is whether he would have been better served with life style modifications and medications rather than stenting for what sounds like minimal coronary artery disease. You can calculate what I would have considered optimal treatment here.
Now my answer to your question:
Basically, you are trying to weigh the potential complications of
- Metformin and low vit. B12 against
- Stent restenosis due to low Vitamin B12.
Some doctors advocate vitamin B12 deficiency screening for people who take metformin, especially if taken for several years or at a high dose. The symptoms of B12 deficiency, particularly those related to neuropathy (numbness, pain, or tingling in hands or feet) would be an indication for treatment. If your husband is not a vegetarian he may get enough vit. B12 with his diet. A daily multivitamin may be more than enough to keep his B12 at normal levels.. Thus, if there is no other choice available than Metformin, the best way forward is to check his vit. B12 blood levels every now and then before recommending treatment.
There are many reasons for stent re-stenosis, most if not all related to other factors than vitamin levels. You have not mentioned the drugs he probably is taking, such as aspirin and plavix and a statin, but I don’t advocate preventive treatment of an unlikely complication that may only occur (if ever) after several years of treatment with Metformin.
Read these articles:
Hope this helps,
I have Pernicious Anaemia treated with 3 monthly Hydroxycobalamin.
I had coronary artery stents after MI in 2006 and have 2 leaking valves..(mitral and aortic)..I am fairly well apart from peripheral neuropathy in feet legs and hands..and constant fatigue ..I have been on a PA support group ..It seem that many people self inject much more than the 3 monthly from a GP.. I was deciding to go along with this until I saw this page…so is it wise or safe for me to do this …I did intend to dicuss with my GP but wanted to try and help myself if I could …Thank you