A high cholesterol and a family history of heart disease. Am I at risk?

Of course you should be concerned. Those numbers are way too high and with your family history you are also at risk! I assume these are not the only factors in your health history that put you at risk.

You should check these links and see what fits your situation:
https://www.cardiachealth.org/heart-information/your-cholesterol
https://www.cardiachealth.org/heart-information/atherosclerosis

I don’t know whether these are issues for you, but check them out:
https://www.cardiachealth.org/heart-information/hypertension
https://www.cardiachealth.org/heart-information/diabetes
https://www.cardiachealth.org/heart-information/metabolic-syndrome

If any of these apply to your situation, you are indeed at risk:
https://www.cardiachealth.org/heart-information/coronary-artery-disease-angina/heart-disease-in-women

Determine your risk:
https://www.cardiachealth.org/risks-benefits/cardiovascular-risk

Hope this helps,
Dr T