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Duchenne's Muscular Dystrophy and heart disease
Patients with Duchenne's Muscular Dystrophy are at a high risk for both arrhythmias and heart failure and should be followed (and treated) agressively.
The heart failure occurs as a "dilated cardiomyopathy", causing "systolic dysfunction":
http://www.cardiachealth.org/ca-blog/heart-function-failure/ (look here for systolic dysfunction).
Treatment often includes angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs)plus Alpha-receptor blockade is clear for cardiomyopathy patients without muscular dystrophy, and there is no reason to avoid this standard regimen in muscular dystrophy patients:
Likewise, arrhythmias if present should be evaluated with monitoring and other testing such as a Holter monitor and possibly another EP study:
Lots of information for you, but I hope this helps,
Ask Doctor T. Blog
If ef was 25% and after 2 yrs it is 50%, should carvedilol be reduced? Carvedilol is 12.5mg 2x with Losartan at 25mg. I exercised during those two years for 30 min four times per week. Started with water aerobics and then treadmill. Added yoga recently.