SYNTAX three year results

Posted on September 15, 2010 - 4:39pm

The latest SYNTAX results extend CABG's superiority over PCI.

SYNTAX was an 1800-patient trial, randomizing patients with left main coronary disease and/or three-vessel disease to either CABG or PCI using the Taxus DES.

This follow-up analysis further clarifies the limited role of PCI in the treatment of triple vessel CAD and/or LMain Stenosis, while the differences have become more obvious.

Key findings included:

  1. Death rates, although higher in the PCI group, were not statistically different
  2. At three years MACCE and MI rates were significantly higher in the PCI group
  3. The difference in Stroke rate between CABG and PCI is leveling off
  4. Only in the lowest-risk patients by SYNTAX score, can both PCI and CABG be considered reasonable options.

 (MACCE: Major Adverse Cardiac and Cerebral Events)

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