Professionals

News analysis & letters to the editor

An approach to Hypertension Treatment In The Elderly

Question: 

Is there a diffence in the treatment of hypertension in the elderly?

In clinic today, I saw an 85 year old woman with Parkinson’s disease for follow-up of her high blood pressure. Her pressures have been difficult to control.

Today her BP is 170/80 with a heart rate of 62 bpm. She is taking an ACEi and a beta-blocker. Her daughter supervises the administration of her medications. She has no known history of heart disease or stroke, and mild renal disease which has been stable. Her EKG shows left ventricular hypertrophy.

Medical therapy often superior than stenting

There is more and more evidence of the superiority of medical therapy over stenting, not only with coronary artery disease, but also with stenotic arteries in your brain: The 30-day rate of stroke or death associated with stenting (14.7%) is nearly 2.5 times as high as the 6% rate associated with stenting in high-risk patients with a 70 - 90 % severe intracranial arterial stenosis.

Left-main PCI is only appropriate for a minority of patients

An atricle published in Cardiovascular Business on November 8, 2011 is very much in-line with our previous publications on this website about optimal treatment of Coronary Artery Disease that includes a Left Main Stenosis and/or three vessel disease:

EuroSCORE II

Comment:

The original EuroSCORE has been replaced with a new model, EuroSCORE II, announced at the EACTS meeting in Lisbon on Monday on 10/3/2011. In this new version, an additional risk factor "Poor mobility" has been added, while others, such as "Obesity" were omitted.

Weight gains after dieting

As is well known, although restriction of diet often results in initial weight loss, more than 80 per cent of obese dieters fail to maintain their reduced weight.

A new study from Australia involved 50 overweight or obese patients without diabetes in a 10-week weight-loss program using a very-low-energy diet. Levels of appetite-regulating hormones were measured at baseline, at the end of the program and one year after initial weight loss.

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft Surgery in Left Main Coronary Artery Disease

In this study, the authors analyzed the combined results of four different randomized clinical trials, comparing PCI with CABG in the treatment of Left Main CAD.

Comparing MACCE (major adverse cardiac or cerebrovascular events) they found “nonsignificantly different 1-year rates of MACCE” between the two treatment modalities after 12 months (14.5% vs. 11.8%, P value 0.11).

The studies included were:

Many patients with coronary artery disease are not treated optimally

As we have reported repeatedly in previews of the SYNTAX trial, the rate of CABG surgeries declined by approximately one-third and that of PCI procedures fell by 4% between 2001 and 2008, according to another study published in JAMA in May, 2011.

The ABCS of Preventing Heart Attacks and Strokes

Each year, more than 2 million Americans have a heart attack or stroke, of whom more than 800,000 of them die; cardiovascular disease is the leading cause of death in the United States and the largest cause of lower life expectancy among blacks.

Progressive Diastolic Dysfunction and Heart Failure is associated with Obesity

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