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Cardiac Defects with a Left to Right Shunt (Acyanotic)
Atrio-Ventricular Septal Defect (AV Canal)
After birth, within the first days of life, the PDA is closed by contractions of its smooth muscles, followed by an intima proliferation. This process is triggered by the postnatal pO2 increase with the first breath of the newborn.
The symptoms of a persisting ductus arteriosus differ according to age:
- In infants with a large PDA increasing cardiac insufficiency with tachypnea, dyspnea, and growth disorders are observed. Drinking weakness, accompanied by increased sweating occur when nursing because this represents a big effort for the newborn.
- In premature infants, an open PDA leads to a flooding of the pulmonary circulation system.
- In older children an open PDA is often discovered accidentally. It seldom leads to a symptom such as infection proneness.
Right heart circulation system is overloaded because blood from the left side always recirculates through the lungs via the ASD.
A VSD may occur by itself but is often associated with other defects.
1 Defect in the membranous part of the interventricular septum
Postnatally, the severity of the VSD depends on its size and the resistance relationships in the pulmonary and systemic circulation systems.
4. Atrio-Ventricular Septal Defect (AV Canal)
This is the most frequently occurring cardiac abnormality in patients with Down syndrome.
1 Defect in the atrial septum
2 Defect in the ventricular septum
Ask Doctor T. Blog
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